A Direct Measurement for LDL-Cholesterol Increases Hypercholesterolemia Prevalence : Comparison with Friedewald Calculation
نویسندگان
چکیده
منابع مشابه
Comparison of LDL cholesterol concentrations by Friedewald calculation and direct measurement in relation to cardiovascular events in 27,331 women.
BACKGROUND National Cholesterol Education Program (NCEP) guidelines recommend development of direct assays for LDL cholesterol (LDL-C) measurement, but it is unclear how these assays compare with Friedewald calculation in predicting cardiovascular disease (CVD). METHODS In a study of 27 331 healthy women with triglycerides <or=4.52 mmol/L (<or=400 mg/dL), baseline fasting Friedewald LDL-C was...
متن کاملComparison of LDL-cholesterol direct measurement with the estimate using the Friedewald formula in a sample of 10,664 patients.
OBJECTIVE To compare direct measurement of LDL-cholesterol (LDL-C) determined by a homogeneous method with LDL-cholesterol estimation determined by the Friedewald formula in a large heterogeneous population. METHODS The measurements of total cholesterol (TC) and triglycerides (TG) were performed using traditional enzymatic methods. The measurements of HDL-C and LDL-C were performed using dire...
متن کاملDirect Measurement of LDL Cholesterol
able amounts of radiolabeled dextran in the plasma protein fraction [15]. Consequently, we do not think this mechanism plays a substantial role in producing the lower than expected dextran concentrations seen in the present study. The dextran we used had a mean molecular mass of 70 000 Da. Thus, some quantity of lower-molecular-mass dextran could have leaked out of the vascular space and distri...
متن کاملComparison of friedewald formula and modified friedewald formula with direct homogeneous assay for low density lipoprotein cholesterol estimation.
OBJECTIVE To compare the Friedewald and modified Friedewald formulae with direct homogeneous assay for serum lowdensity lipoprotein cholesterol (LDL-C) levels estimation. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Armed Forces Institute of Pathology, Rawalpindi, from June to December 2011. METHODOLOGY Healthy subjects of either gender, from Rawalpindi, aged 18-75 year...
متن کاملMeasuring Low Density Lipoprotein Cholesterol: Comparison of Direct Measurement by HiSens Reagents and Friedewald Estimation
BACKGROUND Directly measured low density lipoprotein cholesterol (DLDLC) has been reported to be more accurate than calculated low density lipoprotein cholesterol (CLDLC) using the Friedewald equation. However, some limitations of DLDLC have been reported. In this study, we evaluated differences between CLDLC and DLDLC measured using HiSens reagents. METHODS Data were collected from 582 perso...
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ژورنال
عنوان ژورنال: Journal of UOEH
سال: 2010
ISSN: 0387-821X,2187-2864
DOI: 10.7888/juoeh.32.211